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Pyrogens and Viruses

Bacterial endotoxins also known as pyrogens are lippopolysaccaride molecules attached to cell membaranes of gram negative bacteria.  

Viruses are viewed as non living nucleic acids.

Detection of pyrogens is performed by injecting as sample into test rabbits, and monitoring their body funtions, such as temperature. In some instances they are measured with the more sensitive LAL (Limulus Amoebocyte Lysate) test. Pyrogens can cause fever when used on mammals, and can block cell and tissue growth in cultures.

Distillation/ ultrafiltration/reverse osmosis, and carbon absorption are all methods to remove or reduce pyrogens and viruses in water.  

Primer : Basic Lab Water Contaminants

  • Understanding Suspended Particles
  • All About Colloids
  • Understanding Dissolved Inorganics
  • About Dissolved Organics
  • Dissolved Gasses
  • Understanding Microorganisms
  • About Pyrogens And Viruses
  • Nucleases & DNA

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